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PRMT1 and PRMT4 Regulate Oxidative Stress-Induced Retinal Pigment Epithelial Cell Damage in SIRT1-Dependent and SIRT1-Independent Manners

Oxidative stress-induced retinal pigment epithelial (RPE) cell damage is involved in the progression of diabetic retinopathy. Arginine methylation catalyzed by protein arginine methyltransferases (PRMTs) has emerged as an important histone modification involved in diverse diseases. Sirtuin (SIRT1) i...

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Detalles Bibliográficos
Autores principales: Kim, Dong-Il, Park, Min-Jung, Choi, Joo-Hee, Kim, In-Seon, Han, Ho-Jae, Yoon, Kyung-Chul, Park, Sang-Woo, Lee, Min-Young, Oh, Ki-Seok, Park, Soo-Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4637092/
https://www.ncbi.nlm.nih.gov/pubmed/26583059
http://dx.doi.org/10.1155/2015/617919