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Epithelial to mesenchymal transition is associated with rapamycin resistance

Rapamycin analogues have antitumor efficacy in several tumor types, however few patients demonstrate tumor regression. Thus, there is a pressing need for markers of intrinsic response/resistance and rational combination therapies. We hypothesized that epithelial-to-mesenchymal transition (EMT) confe...

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Detalles Bibliográficos
Autores principales: Holder, Ashley M., Akcakanat, Argun, Adkins, Farrell, Evans, Kurt, Chen, Huiqin, Wei, Caimiao, Milton, Denai R., Li, Yisheng, Do, Kim-Anh, Janku, Filip, Meric-Bernstam, Funda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4637301/
https://www.ncbi.nlm.nih.gov/pubmed/25944619