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Somatic copy number alterations detected by ultra-deep targeted sequencing predict prognosis in oral cavity squamous cell carcinoma

BACKGROUND: Ultra-deep targeted sequencing (UDT-Seq) has advanced our knowledge on the incidence and functional significance of somatic mutations. However, the utility of UDT-Seq in detecting copy number alterations (CNAs) remains unclear. With the goal of improving molecular prognostication and ide...

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Detalles Bibliográficos
Autores principales: Peng, Chien-Hua, Liao, Chun-Ta, Ng, Ka-Pou, Tai, An-Shun, Peng, Shih-Chi, Yeh, Jen-Pao, Chen, Shu-Jen, Tsao, Kuo-Chien, Yen, Tzu-Chen, Hsieh, Wen-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4637328/
https://www.ncbi.nlm.nih.gov/pubmed/26087196