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Novel phenotype in beagle dogs characterized by skin response to compound 48/80 focusing on skin mast cell degranulation
Beagle dogs have long been employed in toxicology studies and as skin disease models. Compared with other experimental animal species, they are known to be susceptible to skin responses, such as rashes, from exposure to various chemical compounds. Here, a unique dog phenotype was identified that sho...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Japanese Association for Laboratory Animal Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4637369/ https://www.ncbi.nlm.nih.gov/pubmed/26062768 http://dx.doi.org/10.1538/expanim.15-0004 |