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Novel phenotype in beagle dogs characterized by skin response to compound 48/80 focusing on skin mast cell degranulation

Beagle dogs have long been employed in toxicology studies and as skin disease models. Compared with other experimental animal species, they are known to be susceptible to skin responses, such as rashes, from exposure to various chemical compounds. Here, a unique dog phenotype was identified that sho...

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Detalles Bibliográficos
Autores principales: Uchida, Mitsuhiro, Ito, Fumi, Tsuchiya, Toshiyuki, Shoji, Yoko, Kurosawa, Toru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Association for Laboratory Animal Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4637369/
https://www.ncbi.nlm.nih.gov/pubmed/26062768
http://dx.doi.org/10.1538/expanim.15-0004