Oncogenic Lmo3 cooperates with Hen2 to induce hydrocephalus in mice

We previously reported that LMO3 and HEN2 act as oncogenes in neuroblastoma development through up-regulating MASH1 transcription by interfering with HES1. To confirm these results in vivo, we generated transgenic mice of these genes. Lmo3 or Hen2 was expressed under the control of Wnt1 promoter, wh...

Descripción completa

Detalles Bibliográficos
Autores principales: Isogai, Eriko, Okumura, Kazuhiro, Saito, Megumi, Yoshizawa, Yasuhiro, Itoh, Kyoko, Tando, So, Ohira, Miki, Haraguchi, Seiki, Nakagawara, Akira, Fushiki, Shinji, Nagase, Hiroki, Wakabayashi, Yuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Association for Laboratory Animal Science 2015
Materias:
Original
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4637378/
https://www.ncbi.nlm.nih.gov/pubmed/26156403
http://dx.doi.org/10.1538/expanim.15-0026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4637378/
https://www.ncbi.nlm.nih.gov/pubmed/26156403
http://dx.doi.org/10.1538/expanim.15-0026

Ejemplares similares