Evaluating Andrographolide as a Potent Inhibitor of NS3-4A Protease and Its Drug-Resistant Mutants Using In Silico Approaches

Current combination therapy of PEG-INF and ribavirin against the Hepatitis C Virus (HCV) genotype-1 infections is ineffective in maintaining sustained viral response in 50% of the infection cases. New compounds in the form of protease inhibitors can complement the combination therapy. Asunaprevir is...

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Detalles Bibliográficos
Autores principales: Chandramohan, Vivek, Kaphle, Anubhav, Chekuri, Mamatha, Gangarudraiah, Sindhu, Bychapur Siddaiah, Gowrishankar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4637434/
https://www.ncbi.nlm.nih.gov/pubmed/26587022
http://dx.doi.org/10.1155/2015/972067

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4637434/
https://www.ncbi.nlm.nih.gov/pubmed/26587022
http://dx.doi.org/10.1155/2015/972067

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