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Size does matter: 18 amino acids at the N-terminal tip of an amino acid transporter in Leishmania determine substrate specificity

Long N-terminal tails of amino acid transporters are known to act as sensors of the internal pool of amino acids and as positive regulators of substrate flux rate. In this study we establish that N-termini of amino acid transporters can also determine substrate specificity. We show that due to alter...

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Detalles Bibliográficos
Autores principales: Schlisselberg, Doreen, Mazarib, Eldar, Inbar, Ehud, Rentsch, Doris, Myler, Peter J., Zilberstein, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4637868/
https://www.ncbi.nlm.nih.gov/pubmed/26549185
http://dx.doi.org/10.1038/srep16289