Cargando…

miR-150 Regulates Differentiation and Cytolytic Effector Function in CD8+ T cells

MicroRNAs regulate most mammalian genes, and they control numerous aspects of immune system development and function. Their precise roles in the CD8+ T cell response, however, remain unclear. In this report, we show that in the absence of the microRNA miR-150, CD8+ T cells fail to undergo robust exp...

Descripción completa

Detalles Bibliográficos
Autores principales: Smith, Norah L., Wissink, Erin M., Grimson, Andrew, Rudd, Brian D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4637875/
https://www.ncbi.nlm.nih.gov/pubmed/26549197
http://dx.doi.org/10.1038/srep16399