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Excess salt exacerbates blood-brain barrier disruption via a p38/MAPK/SGK1-dependent pathway in permanent cerebral ischemia

High salt diet (HSD) is one of the most important risk factors that contribute to many vascular diseases including ischemic stroke. One proposed mechanism underlying the disruption of blood-brain barrier (BBB) mediated by HSD is indirectly through enhancing blood pressure. The direct role of HSD on...

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Detalles Bibliográficos
Autores principales: Zhang, Tongshuai, Fang, Shaohong, Wan, Cong, Kong, Qingfei, Wang, Guangyou, Wang, Shuangshuang, Zhang, Haoqiang, Zou, Haifeng, Sun, Bo, Sun, Wei, Zhang, Yao, Mu, Lili, Wang, Jinghua, Wang, Jing, Zhang, Haiyu, Wang, Dandan, Li, Hulun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4637879/
https://www.ncbi.nlm.nih.gov/pubmed/26549644
http://dx.doi.org/10.1038/srep16548