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Excess salt exacerbates blood-brain barrier disruption via a p38/MAPK/SGK1-dependent pathway in permanent cerebral ischemia
High salt diet (HSD) is one of the most important risk factors that contribute to many vascular diseases including ischemic stroke. One proposed mechanism underlying the disruption of blood-brain barrier (BBB) mediated by HSD is indirectly through enhancing blood pressure. The direct role of HSD on...
Autores principales: | Zhang, Tongshuai, Fang, Shaohong, Wan, Cong, Kong, Qingfei, Wang, Guangyou, Wang, Shuangshuang, Zhang, Haoqiang, Zou, Haifeng, Sun, Bo, Sun, Wei, Zhang, Yao, Mu, Lili, Wang, Jinghua, Wang, Jing, Zhang, Haiyu, Wang, Dandan, Li, Hulun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4637879/ https://www.ncbi.nlm.nih.gov/pubmed/26549644 http://dx.doi.org/10.1038/srep16548 |
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