IL-6 Inhibits Starvation-induced Autophagy via the STAT3/Bcl-2 Signaling Pathway

IL-6, a pleiotropic cytokine, has been investigated for its role in regulating autophagy. Yet, its mechanism of action remains unclear. Here, we show that IL-6 exerted anti-autophagic effects on U937 cells through the STAT3 signaling pathway in vitro. The addition of IL-6 to starved U937 cells signi...

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Detalles Bibliográficos
Autores principales: Qin, Beibei, Zhou, Zhuo, He, Jianqin, Yan, Chunlan, Ding, Shiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4637890/
https://www.ncbi.nlm.nih.gov/pubmed/26549519
http://dx.doi.org/10.1038/srep15701

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4637890/
https://www.ncbi.nlm.nih.gov/pubmed/26549519
http://dx.doi.org/10.1038/srep15701

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