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Viral variants that initiate and drive maturation of V1V2-directed HIV-1 broadly neutralizing antibodies
The elicitation of broadly neutralizing antibodies (bNAbs) is likely to be essential for a preventative HIV-1 vaccine, but this has not yet been achieved by immunization. In contrast some HIV-1-infected individuals naturally mount bNAb responses during chronic infection, suggesting that years of mat...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4637988/ https://www.ncbi.nlm.nih.gov/pubmed/26457756 http://dx.doi.org/10.1038/nm.3963 |