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Molecular insights into the surface-specific arrangement of complement C5 convertase enzymes
BACKGROUND: Complement is a large protein network in plasma that is crucial for human immune defenses and a major cause of aberrant inflammatory reactions. The C5 convertase is a multi-molecular protease complex that catalyses the cleavage of native C5 into its biologically important products. So fa...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4638095/ https://www.ncbi.nlm.nih.gov/pubmed/26552476 http://dx.doi.org/10.1186/s12915-015-0203-8 |