Molecular insights into the surface-specific arrangement of complement C5 convertase enzymes

BACKGROUND: Complement is a large protein network in plasma that is crucial for human immune defenses and a major cause of aberrant inflammatory reactions. The C5 convertase is a multi-molecular protease complex that catalyses the cleavage of native C5 into its biologically important products. So fa...

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Detalles Bibliográficos
Autores principales: Berends, Evelien T. M., Gorham, Ronald D., Ruyken, Maartje, Soppe, Jasper A., Orhan, Hatice, Aerts, Piet C., de Haas, Carla J. C., Gros, Piet, Rooijakkers, Suzan H. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4638095/
https://www.ncbi.nlm.nih.gov/pubmed/26552476
http://dx.doi.org/10.1186/s12915-015-0203-8

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