Combining carbon ion irradiation and non-homologous end-joining repair inhibitor NU7026 efficiently kills cancer cells

BACKGROUND: Our previous data demonstrated that targeting non-homologous end-joining repair (NHEJR) yields a higher radiosensitivity than targeting homologous recombination repair (HRR) to heavy ions using DNA repair gene knockouts (KO) in mouse embryonic fibroblast (MEF). In this study, we determin...

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Detalles Bibliográficos
Autores principales: Ma, Hongyu, Takahashi, Akihisa, Yoshida, Yukari, Adachi, Akiko, Kanai, Tatsuaki, Ohno, Tatsuya, Nakano, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4638098/
https://www.ncbi.nlm.nih.gov/pubmed/26553138
http://dx.doi.org/10.1186/s13014-015-0536-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4638098/
https://www.ncbi.nlm.nih.gov/pubmed/26553138
http://dx.doi.org/10.1186/s13014-015-0536-z

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