Cargando…

Reconstruction of 3D genome architecture via a two-stage algorithm

BACKGROUND: The three-dimensional (3D) configuration of chromosomes within the eukaryote nucleus is an important factor for several cellular functions, including gene expression regulation, and has also been linked with cancer-causing translocation events. While visualization of such architecture re...

Descripción completa

Detalles Bibliográficos
Autores principales: Segal, Mark R., Bengtsson, Henrik L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4638111/
https://www.ncbi.nlm.nih.gov/pubmed/26553003
http://dx.doi.org/10.1186/s12859-015-0799-2