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Reconstruction of 3D genome architecture via a two-stage algorithm
BACKGROUND: The three-dimensional (3D) configuration of chromosomes within the eukaryote nucleus is an important factor for several cellular functions, including gene expression regulation, and has also been linked with cancer-causing translocation events. While visualization of such architecture re...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4638111/ https://www.ncbi.nlm.nih.gov/pubmed/26553003 http://dx.doi.org/10.1186/s12859-015-0799-2 |