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A Broad G Protein-Coupled Receptor Internalization Assay that Combines SNAP-Tag Labeling, Diffusion-Enhanced Resonance Energy Transfer, and a Highly Emissive Terbium Cryptate

Although G protein-coupled receptor (GPCR) internalization has long been considered as a major aspect of the desensitization process that tunes ligand responsiveness, internalization is also involved in receptor resensitization and signaling, as well as the ligand scavenging function of some atypica...

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Detalles Bibliográficos
Autores principales: Levoye, Angélique, Zwier, Jurriaan M., Jaracz-Ros, Agnieszka, Klipfel, Laurence, Cottet, Martin, Maurel, Damien, Bdioui, Sara, Balabanian, Karl, Prézeau, Laurent, Trinquet, Eric, Durroux, Thierry, Bachelerie, Françoise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4638144/
https://www.ncbi.nlm.nih.gov/pubmed/26617570
http://dx.doi.org/10.3389/fendo.2015.00167