Epigenetic regulation of interleukin-8, an inflammatory chemokine, in osteoarthritis

OBJECTIVE: To determine whether altered IL8 methylation status is associated with increased expression of IL8 in human osteoarthritic (OA) chondrocytes. METHODS: IL8 expression levels and the percentage CpG methylation in human chondrocytes were quantified by qRT-PCR and pyrosequencing in OA patient...

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Detalles Bibliográficos
Autores principales: Takahashi, A., de Andrés, M.C., Hashimoto, K., Itoi, E., Oreffo, R.O.C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: W.B. Saunders For The Osteoarthritis Research Society 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4638192/
https://www.ncbi.nlm.nih.gov/pubmed/26521741
http://dx.doi.org/10.1016/j.joca.2015.02.168

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4638192/
https://www.ncbi.nlm.nih.gov/pubmed/26521741
http://dx.doi.org/10.1016/j.joca.2015.02.168

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