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Electroacupuncture Upregulates SIRT1-Dependent PGC-1α Expression in SAMP8 Mice

BACKGROUND: Abnormalities of brain energy metabolism are involved in Alzheimer disease (AD). Sirtuin 1 (SIRT1) is a class III histone deacetylase and activates peroxisome proliferator-activated receptor-γ co-activator-1α (PGC-1α), which enhances mitochondrial biogenesis and energy homeostasis. Elect...

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Detalles Bibliográficos
Autores principales: Dong, Weiguo, Guo, Wanqing, Wang, Feng, Li, Changzheng, Xie, Yongcai, Zheng, Xueha, Shi, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4638282/
https://www.ncbi.nlm.nih.gov/pubmed/26530101
http://dx.doi.org/10.12659/MSM.894864