Anti-emetic drug maropitant induces intestinal motility disorder but not anti-inflammatory action in mice

Maropitant is a neurokinin 1 receptor (NK1R) antagonist that is clinically used as a new anti-emetic drug for dogs. Substance P (SP) and its receptor NK1R are considered to modulate gastrointestinal peristalsis. In addition, SP works as an inflammatory mediator in gastrointestinal diseases. Aim of t...

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Detalles Bibliográficos
Autores principales: MIKAWA, Shoma, YAMAMOTO, Shohei, ISLAM, Md Shafiqul, KAJI, Noriyuki, MURATA, Takahisa, MIZUNO, Risuke, OZAKI, Hiroshi, HORI, Masatoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Veterinary Science 2015
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4638283/
https://www.ncbi.nlm.nih.gov/pubmed/25947563
http://dx.doi.org/10.1292/jvms.15-0182

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4638283/
https://www.ncbi.nlm.nih.gov/pubmed/25947563
http://dx.doi.org/10.1292/jvms.15-0182

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