Novel Etoposide Analogue Modulates Expression of Angiogenesis Associated microRNAs and Regulates Cell Proliferation by Targeting STAT3 in Breast Cancer

Tumor microenvironment play role in angiogenesis and carcinogenesis. Etoposide, a known topoisomerase II inhibitor induces DNA damage resulting in cell cycle arrest. We developed a novel Etoposide analogue, Quinazolino-4β-amidopodophyllotoxin (C-10) that show better efficacy in regulating cell proli...

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Detalles Bibliográficos
Autores principales: Srinivas, Chatla, Ramaiah, M. Janaki, Lavanya, A., Yerramsetty, Suresh, Kavi Kishor, P. B, Basha, Shaik Anver, Kamal, Ahmed, Bhadra, Utpal, Bhadra, Manika-Pal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4638343/
https://www.ncbi.nlm.nih.gov/pubmed/26551008
http://dx.doi.org/10.1371/journal.pone.0142006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4638343/
https://www.ncbi.nlm.nih.gov/pubmed/26551008
http://dx.doi.org/10.1371/journal.pone.0142006

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