PACE4 regulates apoptosis in human prostate cancer cells via endoplasmic reticulum stress and mitochondrial signaling pathways

BACKGROUND: PACE4 is a proprotein convertase capable of processing numerous substrates involved in tumor growth, invasion, and metastasis. However, the precise role of PACE4 during prostate cancer cell apoptosis has not been reported. METHODS: In the present study, human prostate cancer cell lines D...

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Detalles Bibliográficos
Autores principales: Yao, Zhiyong, Sun, Bin, Hong, Quan, Yan, Jingmin, Mu, Dawei, Li, Jianye, Sheng, Haibo, Guo, Heqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4639519/
https://www.ncbi.nlm.nih.gov/pubmed/26604689
http://dx.doi.org/10.2147/DDDT.S86881

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4639519/
https://www.ncbi.nlm.nih.gov/pubmed/26604689
http://dx.doi.org/10.2147/DDDT.S86881

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