Enhanced bioavailability of nerve growth factor with phytantriol lipid-based crystalline nanoparticles in cochlea

PURPOSE: Supplementation of exogenous nerve growth factor (NGF) into the cochlea of deafened animals rescues spiral ganglion cells from degeneration. However, a safe and potent delivery of therapeutic proteins, such as NGF, to spiral ganglion cells remains one of the greatest challenges. This study...

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Detalles Bibliográficos
Autores principales: Bu, Meng, Tang, Jingling, Wei, Yinghui, Sun, Yanhui, Wang, Xinyu, Wu, Linhua, Liu, Hongzhuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4639561/
https://www.ncbi.nlm.nih.gov/pubmed/26604754
http://dx.doi.org/10.2147/IJN.S82944

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4639561/
https://www.ncbi.nlm.nih.gov/pubmed/26604754
http://dx.doi.org/10.2147/IJN.S82944

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