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Anti-proliferative activity and cell cycle arrest induced by evodiamine on paclitaxel-sensitive and -resistant human ovarian cancer cells

Chemo-resistance is the main factor for poor prognosis in human ovarian epithelial cancer. Active constituents derived from Chinese medicine with anti-cancer potential might circumvent this obstacle. In our present study, evodiamine (EVO) derived from Evodia rutaecarpa (Juss.) Benth suppressed the p...

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Detalles Bibliográficos
Autores principales: Zhong, Zhang-Feng, Tan, Wen, Wang, Sheng-Peng, Qiang, Wen-An, Wang, Yi-Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4639765/
https://www.ncbi.nlm.nih.gov/pubmed/26553648
http://dx.doi.org/10.1038/srep16415