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Risperidone and NAP protect cognition and normalize gene expression in a schizophrenia mouse model

Mutated disrupted in schizophrenia 1 (DISC1), a microtubule regulating protein, leads to schizophrenia and other psychiatric illnesses. It is hypothesized that microtubule stabilization may provide neuroprotection in schizophrenia. The NAP (NAPVSIPQ) sequence of activity-dependent neuroprotective pr...

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Detalles Bibliográficos
Autores principales: Vaisburd, Sinaya, Shemer, Zeev, Yeheskel, Adva, Giladi, Eliezer, Gozes, Illana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4639790/
https://www.ncbi.nlm.nih.gov/pubmed/26553741
http://dx.doi.org/10.1038/srep16300