A Holistic Multi Evidence Approach to Study the Fragmentation Behaviour of Crystalline Mannitol

Mannitol is an essential excipient employed in orally disintegrating tablets due to its high palatability. However its fundamental disadvantage is its fragmentation during direct compression, producing mechanically weak tablets. The primary aim of this study was to assess the fracture behaviour of c...

Descripción completa

Detalles Bibliográficos
Autores principales: Koner, Jasdip S., Rajabi-Siahboomi, Ali, Bowen, James, Perrie, Yvonne, Kirby, Daniel, Mohammed, Afzal R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4639810/
https://www.ncbi.nlm.nih.gov/pubmed/26553127
http://dx.doi.org/10.1038/srep16352

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4639810/
https://www.ncbi.nlm.nih.gov/pubmed/26553127
http://dx.doi.org/10.1038/srep16352

Ejemplares similares