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Cargo-selective apical exocytosis in epithelial cells is conducted by Myo5B, Slp4a, Vamp7, and Syntaxin 3

Mutations in the motor protein Myosin Vb (Myo5B) or the soluble NSF attachment protein receptor Syntaxin 3 (Stx3) disturb epithelial polarity and cause microvillus inclusion disease (MVID), a lethal hereditary enteropathy affecting neonates. To understand the molecular mechanism of Myo5B and Stx3 in...

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Detalles Bibliográficos
Autores principales: Vogel, Georg F., Klee, Katharina M.C., Janecke, Andreas R., Müller, Thomas, Hess, Michael W., Huber, Lukas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4639860/
https://www.ncbi.nlm.nih.gov/pubmed/26553929
http://dx.doi.org/10.1083/jcb.201506112