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GRHL2 coordinates regeneration of a polarized mucociliary epithelium from basal stem cells

Pseudostratified airway epithelium of the lung is composed of polarized ciliated and secretory cells maintained by basal stem/progenitor cells. An important question is how lineage choice and differentiation are coordinated with apical–basal polarity and epithelial morphogenesis. Our previous studie...

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Detalles Bibliográficos
Autores principales: Gao, Xia, Bali, Aman S., Randell, Scott H., Hogan, Brigid L.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4639861/
https://www.ncbi.nlm.nih.gov/pubmed/26527742
http://dx.doi.org/10.1083/jcb.201506014