Ubiquitin ligase TRIM3 controls hippocampal plasticity and learning by regulating synaptic γ-actin levels

Synaptic plasticity requires remodeling of the actin cytoskeleton. Although two actin isoforms, β- and γ-actin, are expressed in dendritic spines, the specific contribution of γ-actin in the expression of synaptic plasticity is unknown. We show that synaptic γ-actin levels are regulated by the E3 ub...

Descripción completa

Detalles Bibliográficos
Autores principales: Schreiber, Joerg, Végh, Marlene J., Dawitz, Julia, Kroon, Tim, Loos, Maarten, Labonté, Dorthe, Li, Ka Wan, Van Nierop, Pim, Van Diepen, Michiel T., De Zeeuw, Chris I., Kneussel, Matthias, Meredith, Rhiannon M., Smit, August B., Van Kesteren, Ronald E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4639863/
https://www.ncbi.nlm.nih.gov/pubmed/26527743
http://dx.doi.org/10.1083/jcb.201506048

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4639863/
https://www.ncbi.nlm.nih.gov/pubmed/26527743
http://dx.doi.org/10.1083/jcb.201506048

Ejemplares similares