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Cdc42-dependent actin dynamics controls maturation and secretory activity of dendritic cells

Cell division cycle 42 (Cdc42) is a member of the Rho guanosine triphosphatase family and has pivotal functions in actin organization, cell migration, and proliferation. To further study the molecular mechanisms of dendritic cell (DC) regulation by Cdc42, we used Cdc42-deficient DCs. Cdc42 deficienc...

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Detalles Bibliográficos
Autores principales: Schulz, Anna M., Stutte, Susanne, Hogl, Sebastian, Luckashenak, Nancy, Dudziak, Diana, Leroy, Céline, Forné, Ignasi, Imhof, Axel, Müller, Stephan A., Brakebusch, Cord H., Lichtenthaler, Stefan F., Brocker, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4639873/
https://www.ncbi.nlm.nih.gov/pubmed/26553928
http://dx.doi.org/10.1083/jcb.201503128