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Enhancement of Solubility of Lamotrigine by Solid Dispersion and Development of Orally Disintegrating Tablets Using 3(2) Full Factorial Design

Present investigation deals with the preparation and evaluation of orally disintegrating tablets (ODTs) of lamotrigine using β-cyclodextrin and PVP-K30 as polymers for the preparation of solid dispersion which help in enhancement of aqueous solubility of this BCS CLASS-II drug and sodium starch glyc...

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Detalles Bibliográficos
Autores principales: Singh, Jatinderpal, Garg, Rajeev, Gupta, Ghanshyam Das
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4639876/
https://www.ncbi.nlm.nih.gov/pubmed/26634173
http://dx.doi.org/10.1155/2015/828453