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The γ-tubulin-specific inhibitor gatastatin reveals temporal requirements of microtubule nucleation during the cell cycle

Inhibitors of microtubule (MT) assembly or dynamics that target α/β-tubulin are widely exploited in cancer therapy and biological research. However, specific inhibitors of the MT nucleator γ-tubulin that would allow testing temporal functions of γ-tubulin during the cell cycle are yet to be identifi...

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Detalles Bibliográficos
Autores principales: Chinen, Takumi, Liu, Peng, Shioda, Shuya, Pagel, Judith, Cerikan, Berati, Lin, Tien-chen, Gruss, Oliver, Hayashi, Yoshiki, Takeno, Haruka, Shima, Tomohiro, Okada, Yasushi, Hayakawa, Ichiro, Hayashi, Yoshio, Kigoshi, Hideo, Usui, Takeo, Schiebel, Elmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640066/
https://www.ncbi.nlm.nih.gov/pubmed/26503935
http://dx.doi.org/10.1038/ncomms9722