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Autophagy and endosomal trafficking inhibition by Vibrio cholerae MARTX toxin phosphatidylinositol-3-phosphate-specific phospholipase A1 activity

Vibrio cholerae, responsible for acute gastroenteritis secretes a large multifunctional-autoprocessing repeat-in-toxin (MARTX) toxin linked to evasion of host immune system, facilitating colonization of small intestine. Unlike other effector domains of the multifunctional toxin that target cytoskele...

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Detalles Bibliográficos
Autores principales: Agarwal, Shivani, Kim, Hyunjin, Chan, Robin B., Agarwal, Shivangi, Williamson, Rebecca, Cho, Wonhwa, Paolo, Gilbert D., Satchell, Karla J. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640098/
https://www.ncbi.nlm.nih.gov/pubmed/26498860
http://dx.doi.org/10.1038/ncomms9745