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Inferring intra-motif dependencies of DNA binding sites from ChIP-seq data
BACKGROUND: Statistical modeling of transcription factor binding sites is one of the classical fields in bioinformatics. The position weight matrix (PWM) model, which assumes statistical independence among all nucleotides in a binding site, used to be the standard model for this task for more than t...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640111/ https://www.ncbi.nlm.nih.gov/pubmed/26552868 http://dx.doi.org/10.1186/s12859-015-0797-4 |