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Inferring intra-motif dependencies of DNA binding sites from ChIP-seq data

BACKGROUND: Statistical modeling of transcription factor binding sites is one of the classical fields in bioinformatics. The position weight matrix (PWM) model, which assumes statistical independence among all nucleotides in a binding site, used to be the standard model for this task for more than t...

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Detalles Bibliográficos
Autores principales: Eggeling, Ralf, Roos, Teemu, Myllymäki, Petri, Grosse, Ivo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640111/
https://www.ncbi.nlm.nih.gov/pubmed/26552868
http://dx.doi.org/10.1186/s12859-015-0797-4

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