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Biosynthesis of the mycotoxin tenuazonic acid by a fungal NRPS–PKS hybrid enzyme

Tenuazonic acid (TeA) is a well-known mycotoxin produced by various plant pathogenic fungi. However, its biosynthetic gene has been unknown to date. Here we identify the TeA biosynthetic gene from Magnaporthe oryzae by finding two TeA-inducing conditions of a low-producing strain. We demonstrate tha...

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Detalles Bibliográficos
Autores principales: Yun, Choong-Soo, Motoyama, Takayuki, Osada, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640141/
https://www.ncbi.nlm.nih.gov/pubmed/26503170
http://dx.doi.org/10.1038/ncomms9758