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The PDK1–Rsk Signaling Pathway Controls Langerhans Cell Proliferation and Patterning

Langerhans cells (LC), the dendritic cells of the epidermis, are distributed in a distinctive regularly spaced array. In the mouse, the LC array is established in the first few days of life from proliferating local precursors, but the regulating signaling pathways are not fully understood. We found...

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Detalles Bibliográficos
Autores principales: Zaru, Rossana, Matthews, Stephen P., Edgar, Alexander J., Prescott, Alan R., Gomez-Nicola, Diego, Hanauer, André, Watts, Colin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AAI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640173/
https://www.ncbi.nlm.nih.gov/pubmed/26401001
http://dx.doi.org/10.4049/jimmunol.1501520