HSPB1 as a Novel Regulator of Ferroptotic Cancer Cell Death

Ferroptosis is an iron-dependent form of non-apoptotic cell death, but its molecular mechanism remains largely unknown. Here, we demonstrate that heat shock protein beta-1 (HSPB1) is a negative regulator of ferroptotic cancer cell death. Erastin, a specific ferroptosis-inducing compound, stimulates...

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Detalles Bibliográficos
Autores principales: Sun, Xiaofang, Ou, Zhanhui, Xie, Min, Kang, Rui, Fan, Yong, Niu, Xiaohua, Wang, Haichao, Cao, Lizhi, Tang, Daolin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640181/
https://www.ncbi.nlm.nih.gov/pubmed/25728673
http://dx.doi.org/10.1038/onc.2015.32

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640181/
https://www.ncbi.nlm.nih.gov/pubmed/25728673
http://dx.doi.org/10.1038/onc.2015.32

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