Variant mapping and mutation discovery in inbred mice using next-generation sequencing

BACKGROUND: The development of powerful new methods for DNA sequencing enable the discovery of sequence variants, their utilization for the mapping of mutant loci, and the identification of causal variants in a single step. We have applied this approach for the analysis of ENU-mutagenized mice maint...

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Detalles Bibliográficos
Autores principales: Gallego-Llamas, Jabier, Timms, Andrew E., Geister, Krista A., Lindsay, Anna, Beier, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640199/
https://www.ncbi.nlm.nih.gov/pubmed/26552429
http://dx.doi.org/10.1186/s12864-015-2173-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640199/
https://www.ncbi.nlm.nih.gov/pubmed/26552429
http://dx.doi.org/10.1186/s12864-015-2173-1

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