Genomic profiling of CHEK2*1100delC-mutated breast carcinomas

BACKGROUND: CHEK2*1100delC is a moderate-risk breast cancer susceptibility allele with a high prevalence in the Netherlands. We performed copy number and gene expression profiling to investigate whether CHEK2*1100delC breast cancers harbor characteristic genomic aberrations, as seen for BRCA1 mutate...

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Detalles Bibliográficos
Autores principales: Massink, Maarten P. G., Kooi, Irsan E., Martens, John W. M., Waisfisz, Quinten, Meijers-Heijboer, Hanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640207/
https://www.ncbi.nlm.nih.gov/pubmed/26553136
http://dx.doi.org/10.1186/s12885-015-1880-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640207/
https://www.ncbi.nlm.nih.gov/pubmed/26553136
http://dx.doi.org/10.1186/s12885-015-1880-y

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