Identification and characterization of human nucleus pulposus cell specific serotypes of adeno-associated virus for gene therapeutic approaches of intervertebral disc disorders

BACKGROUND: Intervertebral disc (IVD) disorders are often accompanied by painful inflammatory and immunopathological processes. Nucleus pulposus (NP) cells play a pivotal role in maintenance of IVD by organizing the expression of anabolic, catabolic, anti-catabolic and inflammatory cytokines. Human...

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Detalles Bibliográficos
Autores principales: Mern, Demissew S., Thomé, Claudius
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640218/
https://www.ncbi.nlm.nih.gov/pubmed/26552484
http://dx.doi.org/10.1186/s12891-015-0799-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640218/
https://www.ncbi.nlm.nih.gov/pubmed/26552484
http://dx.doi.org/10.1186/s12891-015-0799-4

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