Effect of a high-dose target-controlled naloxone infusion on pain and hyperalgesia in patients following groin hernia repair: study protocol for a randomized controlled trial

BACKGROUND: Central sensitization is modulated by the endogenous opioid system and plays a major role in the development and maintenance of pain. Recent animal studies performed following resolution of inflammatory pain showed reinstatement of tactile hypersensitivity induced by administration of a...

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Detalles Bibliográficos
Autores principales: Pereira, Manuel Pedro, Utke Werner, Mads, Berg Dahl, Joergen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640219/
https://www.ncbi.nlm.nih.gov/pubmed/26554360
http://dx.doi.org/10.1186/s13063-015-1021-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640219/
https://www.ncbi.nlm.nih.gov/pubmed/26554360
http://dx.doi.org/10.1186/s13063-015-1021-6

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