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Bayesian modeling suggests that IL-12 (p40), IL-13 and MCP-1 drive murine cytokine networks in vivo

BACKGROUND: Cytokine-hormone network deregulations underpin pathologies ranging from autoimmune disorders to cancer, but our understanding of these networks in physiological/pathophysiological states remains patchy. We employed Bayesian networks to analyze cytokine-hormone interactions in vivo using...

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Detalles Bibliográficos
Autores principales: Field, Sarah L., Dasgupta, Tathagata, Cummings, Michele, Savage, Richard S., Adebayo, Julius, McSara, Hema, Gunawardena, Jeremy, Orsi, Nicolas M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640223/
https://www.ncbi.nlm.nih.gov/pubmed/26553024
http://dx.doi.org/10.1186/s12918-015-0226-3