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Bayesian modeling suggests that IL-12 (p40), IL-13 and MCP-1 drive murine cytokine networks in vivo
BACKGROUND: Cytokine-hormone network deregulations underpin pathologies ranging from autoimmune disorders to cancer, but our understanding of these networks in physiological/pathophysiological states remains patchy. We employed Bayesian networks to analyze cytokine-hormone interactions in vivo using...
Autores principales: | Field, Sarah L., Dasgupta, Tathagata, Cummings, Michele, Savage, Richard S., Adebayo, Julius, McSara, Hema, Gunawardena, Jeremy, Orsi, Nicolas M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640223/ https://www.ncbi.nlm.nih.gov/pubmed/26553024 http://dx.doi.org/10.1186/s12918-015-0226-3 |
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