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Autophagy contributes to the chemo-resistance of non-small cell lung cancer in hypoxic conditions

BACKGROUND: The development of chemo-resistance in non-small lung cancer is a major obstacle in treating patients. Hypoxia is a commonly faced microenvironment in solid tumor and suggested to be related to both autophagy and chemo-resistance. METHODS: In this study, we investigated the role of hypox...

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Detalles Bibliográficos
Autores principales: Lee, Jin Gu, Shin, Ju Hye, Shim, Hyo Sup, Lee, Chang Young, Kim, Dae Joon, Kim, Young Sam, Chung, Kyung Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640373/
https://www.ncbi.nlm.nih.gov/pubmed/26553068
http://dx.doi.org/10.1186/s12931-015-0285-4