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Inhibiting inducible miR-223 further reduces viable cells in human cancer cell lines MCF-7 and PC3 treated by celastrol

BACKGROUND: Celastrol is a novel anti-tumor agent. Ways to further enhance this effect of celastrol has attracted much research attention. METHODS AND RESULTS: Here, we report that celastrol treatment can elevate miR-223 in human breast cancer cell line MCF-7 and prostate cancer PC3. Down-regulating...

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Detalles Bibliográficos
Autores principales: Cao, Lu, Zhang, Xue, Cao, Fanfan, Wang, Ying, Shen, Yufan, Yang, Chunxin, Uzan, Georges, Peng, Bin, Zhang, Denghai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640397/
https://www.ncbi.nlm.nih.gov/pubmed/26552919
http://dx.doi.org/10.1186/s12885-015-1909-2