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Hepatic myofibroblasts derived from Schistosoma mansoni-infected mice are a source of IL-5 and eotaxin: controls of eosinophil populations in vitro

BACKGROUND: Hepatic myofibroblasts are relevant for pathogenesis of S. mansoni infection. In normal liver, these perisinusoidal cells are quiescent, express the lipocyte phenotype, and are located in the Disse’s space, being the major site of vitamin A storage. When activated, they convert to myofib...

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Detalles Bibliográficos
Autores principales: Paiva, Ligia Almeida, Brand, Camila, Bandeira-Melo, Christianne, Bozza, Patricia Torres, El-Cheikh, Marcia Cury, Silva, Patricia Martins, Borojevic, Radovan, Perez, Sandra Aurora Chavez
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640404/
https://www.ncbi.nlm.nih.gov/pubmed/26552582
http://dx.doi.org/10.1186/s13071-015-1197-3