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No up-regulation of the phosphatidylethanolamine N-methyltransferase pathway and choline production by sex hormones in cats

BACKGROUND: Feline hepatic lipidosis (FHL) is a common cholestatic disease affecting cats of any breed, age and sex. Both choline deficiency and low hepatic phosphatidylethanolamine N-methyltransferase (PEMT) activity are associated with hepatic lipidosis (HL) in humans, mice and rats. The PEMT expr...

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Detalles Bibliográficos
Autores principales: Valtolina, Chiara, Vaandrager, Arie B., Favier, Robert P., Robben, Joris H., Tuohetahuntila, Maidina, Kummeling, Anne, Jeusette, Isabelle, Rothuizen, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640414/
https://www.ncbi.nlm.nih.gov/pubmed/26552767
http://dx.doi.org/10.1186/s12917-015-0591-6