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Triptolide Inhibited Cytotoxicity of Differentiated PC12 Cells Induced by Amyloid-Beta(25–35) via the Autophagy Pathway
Evidence shows that an abnormal deposition of amyloid beta-peptide(25–35) (Aβ(25–35)) was the primary cause of the pathogenesis of Alzheimer’s disease (AD). And the elimination of Aβ(25–35) is considered an important target for the treatment of AD. Triptolide (TP), isolated from Tripterygium wilford...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640509/ https://www.ncbi.nlm.nih.gov/pubmed/26554937 http://dx.doi.org/10.1371/journal.pone.0142719 |